Gout is a type of inflammatory arthritis that develops when the body has high uric acid levels, known as hyperuricemia. Gout often affects the big toe but can also affect other joints, including ...

During an acute attack of gout, inflammatory mediators are released and vascular adhesion and chemotaxis of leukocytes to the inflamed joint is enhanced. 7 However, for this to have an impact on ...

According to Mayo Clinic, gout symptoms typically appear "suddenly" at night. You may feel intense joint pain, specifically in your big toe. However, other joints can be affected, including the ...