The following is a summary of “Role of glucocorticoid receptor expression in Chronic Chagas Cardiomyopathy: implications for ...

Corticosteroid signaling by glucocorticoids is mediated through two distinct intracellular receptor subtypes referred as the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR ...

ABBV-154, an antibody-drug conjugate comprising adalimumab conjugated to a proprietary glucocorticoid receptor modulator, shows potential for extending flare-free periods in patients with ...

In the cell, the hormone acts by binding to the glucocorticoid receptor (GR), which then acts as a transcription factor to regulate the activity of certain target genes. In order to switch off the ...

The activation of FLT3 promotes the proliferation mechanisms of the cell, a hallmark of cancer, one of which is the inactivation of the glucocorticoid receptor, rendering the cell insensitive to ...