The common feature of this glucocorticoid-resistant B-ALL subtype is the rearrangement of the MLL gene. This means that a DNA fragment with this gene has moved elsewhere in the genome, in a sort ...

ABBV-154, an antibody-drug conjugate comprising adalimumab conjugated to a proprietary glucocorticoid receptor modulator, shows potential for extending flare-free periods in patients with ...

Long-term use of glucocorticoids (GCs) for the treatment of lupus is very common, however, it has also been associated with side effects like high blood pressure, diabetes, infection, and osteoporosis ...

A recent study found that combined tocilizumab and glucocorticoid therapy for at least 6 months did not fully eliminate ...

Corticosteroid signaling by glucocorticoids is mediated through two distinct intracellular receptor subtypes referred as the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR ...

The following is a summary of “Role of glucocorticoid receptor expression in Chronic Chagas Cardiomyopathy: implications for ...

There's a downside to being a powerful alpha male -- at least if you're a baboon. Studies show that despite their high rank, the No. 1 males in baboon society are also some of the most stressed out, ...

A pilot study in 19 LGMD patients and one with Becker MD found low-dose prednisone helped lower markers of muscle damage and inflammation.