Up to 20% of patients requiring mechanical ventilation will suffer from difficult weaning (the need of more than 7 days of weaning after the first spontaneous breathing trial), which may depend on ...

N Engl J Med 2000; 342:1471-1477 The transition from mechanical ventilator support to spontaneous breathing has traditionally been called weaning. Most efforts to expedite weaning have focused on ...

The diaphragm is the primary muscle responsible for breathing, and its impairment can complicate the weaning process from mechanical ventilation. Recent research has focused on understanding ...