1月8日Nature的研究报道“Precursors of exhausted T cells are preemptively formed in acute infection”，通过多种实验技术，包括单细胞RNA测序（scRNA-seq）、流式细胞术 ...

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its ...

Researchers have identified a rare type of immune cells that hold the key to maintaining long-term immune responses.

known as a T cell, becomes exhausted, according to a new study that points the way for important new lines of investigation. The study's authors knew the immune system was dysregulated in patients ...

By screening FDA-approved drugs, they discovered that miltefosine—a small molecule previously used to treat leishmaniasis—could restore the functionality of exhausted CAR-T cells. Remarkably ...

Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune ...

Yet they exhausted themselves faster than naïve cells. While naïve T cells lacked the disease-fighting imprinting of memory cells, they became more effective when RUNX2 was added. They also ...

A new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled "Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells." ...