Epigenetics, which determines how genes are expressed, may prove an exception. There is a growing awareness that epigenetic dysregulation plays a significant role in many types of cancer ...
How the epigenetic machinery regulates these monoamine ... unlike serotonylated H3Q5 (H3Q5ser), which enhances the binding of the reader protein WDR5 to histone H3 4, 5, H3Q5his decreases WDR5 ...
Among important epigenetic players are >60 human protein methyltransferases (PMTs), > 30 protein lysine demethylases (KDMs), and various methyl-arginine/lysine (Rme/Kme) reader proteins. These ...