This historical perspective integrates 50 years of research on SOS mutagenesis in Escherichia coli with the proverbial ... recombination—that feature DNA polymerase V. Genetic and biochemical ...

They were particularly drawn to features of T7 DNA polymerase—derived from the T7 bacteriophage that infects Escherichia coli—due to its ability to synthesize long stretches of DNA by binding and ...

New research reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli ... the RNA polymerase (RNAP) enzyme responsible for copying DNA into RNA can generate rampant R-loops ...

The findings demonstrate that, under certain circumstances, the RNA polymerase (RNAP) enzyme responsible for copying DNA into RNA can ... group found that E. coli exposed to stressful, high ...

An R-loop occurs when newly synthesized RNA binds back to its DNA template ... the enzyme RapA stops R-loop formation in E. coli. This has significant ramifications for how all cells preserve ...

The researchers watched replicating DNA from E. coli bacteria. The first step in ... different strands in opposite directions worked. The polymerase on the “leading strand” can easily work ...

With a PhD in Genetics and Genomics, Niki channels her infectious disease research and science communication experiences into her role as a senior science editor for the TS Creative Services team.