In each cell cycle, the integrity of genetic and epigenetic information is challenged during DNA replication. When DNA replicates, chromatin undergoes a wave of disruption and subsequent ...

During DNA replication, the unwinding of strands leaves ... is wrong" and this also holds true for other phases of the cell cycle. In other words, whether ssDNA is created during replication ...

Harvest cells, want good single cell suspension Count cells Dispense aliquots of 1 million cells into labeled tubes Add 5 ml PBS and centrifuge for 5 min at 400 x g. Re-suspend cell pellet in 300 ul ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

In the course of growth and division, eukaryotic cells duplicate their genomes with remarkable fidelity. The precision of this process depends in large measure upon stringent regulatory mechanisms ...

When looking at cells with a microscope, the length of different stages of the cell cycle can be estimated using the formula: \(\text{Length of time in phase}=\) \(\frac{\text{observed number of ...

Replication of DNA DNA replication is the process by which a cell makes an identical copy of its DNA. Gene expression Only a fraction of the genes possessed by any particular cell will be expressed.

“If you impose a structure on it, which is this replication-driven cell cycle structure, then suddenly it goes from being incredibly noisy ... They have multiple, larger chromosomes, multiple origins ...

We also discovered that this breakage mechanism only occurs at the beginning of the cell cycle phase, when DNA replication ...

TAg expression and viral replication occurred after the first round of host DNA replication, and TAg expression also depended on the cell's going through a first round of replication. If Needham ...

The following is a summary of “Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma,” published in the January 2025 issue of Urology by Chen et al. Clear cell ...