Sperm DNA damage is a marker of outcome for both spontaneous pregnancy and assisted reproduction techniques, and as such is an important clinical parameter for men undergoing fertility evaluation.

The researchers used preclinical models to explore the impact of stress on aging. They observed that social stress activates neurons in the hippocampus and cortex, showing signs of senescence and DNA ...

A hidden DNA marker puts people at significantly greater ... in chromosomes which have protective caps at the end to prevent damage, known as telomeres. Now scientists have found that people ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

In mice exposed to chronic social stress, the researchers found elevated levels of DNA damage markers. This damage likely triggers the cellular machinery responsible for activation of a senescence ...

The study is published in Nature Structural & Molecular Biology in an article titled, “ATM and IRAK1 orchestrate two distinct mechanisms of NF-κB activation in response to DNA damage.” ...

Most dividing cells in the body have well-defined checkpoint mechanisms to sense and correct DNA damage during DNA replication. Neurons, however, do not divide. For this reason, they are at ...

Explore how cfDNA levels change around colorectal cancer surgery and their potential as non-invasive biomarkers for ...

A new research paper was published in Oncotarget’s Volume 16 on January 21, 2025, titled “Assessment of cfDNA release ...