Out-of-whack cortisol levels can seriously affect your daily life. Here are the symptoms and how doctors recommend fixing it.

Unfortunately, trends are rarely as simple as they appear and may have people jumping into action before learning what ...

Each time a person undergoes stress the brain releases cortisol hormones. Cortisol binds to glucocorticoid receptors and tells the body to prepare its “fight-or-flight” response. This hormone also ...

This receptor signals the cells in the zona fasciculata of the adrenal cortex to synthesize and secrete glucocorticoids (cortisol in humans, corticosterone in rodents). Secretion of ...

Blockade of cortisol receptors by mifepristone can result in an uncontrolled production and release of an excess of these proinflammatory mediators. Mifepristone's ability to block cortisol ...

About Relacorilant Relacorilant is a selective cortisol modulator that binds to the glucocorticoid receptor but not to the body's other hormone receptors. Corcept is studying relacorilant in a ...

Urine-free cortisol was evaluated at 6 months for response ... for improvement in glucose control is desirable. Glucocorticoid receptor antagonists (mifepristone) and somatostatin receptor ...

The activation of the adenosine A2A receptor, which is mediated by the inhibition of adenosine A1 receptor, has been associated with depression-like behavior and anhedonia. High levels of cortisol, ...