Investigating survival outcomes in patients with early- vs late-onset colorectal cancer with liver metastases. Summary of associations between the colorectal tumor T cell response and sex. *A total of ...

View Full Profile. Learn about our Editorial Policies. Colorectal cancers, which kill more than 900,000 people each year, are notoriously heterogeneous. The cell type and the genetic mutations that ...

Oncolytic viruses (OVs) are viruses that infect and kill cancer cells while sparing healthy tissue, making them a promising therapeutic option in cancer ...

A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage ...

CAFs, cancer-associated fibroblasts; CAR-T, chimeric antigen receptor-T; CRC, colorectal cancer; ECM, extracellular matrix; MDSCs, myeloid-derived suppressor cells; TAMs, tumor-associated macrophages; ...

Nevertheless, the understanding of the intricate relationship between dysfunctional CD8 + T cells within the tumor ...

University of Galway’s Dr Aideen Ryan is looking at mechanisms in supportive tissue cells with the aim of enhancing the ...

Prof. MENG Guangxun's team from the Shanghai Institute of Immunity and Infection of the Chinese Academy of Sciences, and collaborators, have revealed a novel mechanism whereby a short form of IL-18, ...

SAN DIEGO and SUZHOU, China - Adagene Inc. (NASDAQ: ADAG), a biotechnology firm with a market capitalization of $85 million focused on antibody-based cancer therapies, has revealed encouraging ...

they found that it silenced those immune suppression genes (essentially un-silencing or re-activating the immune system), remodeled the microenvironment, and boosted antitumor immune responses. The ...

"What is a tumor?" This is the fundamental question to answer if we want to treat cancer effectively. Our vision of cancer ...