Cold-inducible RNA-binding protein (CIRP) is a significant player in cellular stress responses and inflammation. It is classified as a damage-associated molecular pattern (DAMP), which means it ...
To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...
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