A diverse set of cytoskeletal reorganization genes exhibit cell-cycle–dependent regulation, indicating that biological pathways are redirected for the execution of cell division. Many genes ...

Cell cycle progression at the G 1 to S phase transition ... complex might need to be initiated by the pre-BCR. Figure 4: Regulation of IgL gene recombination by the PI3K–PKB–FOXO pathway.

Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin organization and cell cycle state, including quiescence. Gene expression is important because a specific ...

An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

Previous studies have shown that this modification is required for the dynamic regulation of essential cellular functions, such as the cell's life cycle, and even how cells break down sugar to ...