We were also the first to report that tumor growth induces monocyte-derived tumor-associated macrophages (TAMs) supported by juxtacrine Notch signaling by cancer cells. We found that TAMs can be ...

PMB212 blocks most of the signaling pathways related to cancer stemness in cells, including those mediated by Wnt, Notch, Hedgehog, Hippo, and STAT3. Moreover, PMB212 prevents epithelial to ...

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system.

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the ...

Abdera Therapeutics Inc., a clinical-stage biopharmaceutical company leveraging its advanced antibody engineering ROVEr™ platform to design and develop tunable precision radiopharmaceuticals for ...