Advances in CRISPR technologies promise to accelerate the burgeoning pipeline of gene-editing therapies and broaden access to these disease-altering therapies.

The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...

CRISPR places an entirely new kind of power into human hands. For the first time, scientists can quickly and precisely alter, delete, and rearrange the DNA of nearly any living organism ...

Using this method, Samuel demonstrated that if the anti-defense genes are positioned near the DNA entry point, the plasmid successfully overcomes the CRISPR system. However, if these genes are ...

Early reports have demonstrated that CRISPR effectively excises integrated human immunodeficiency virus type 1 (HIV) from cells. 1,2 For Michele Lai from the University of Pisa, these studies raised ...

Bring up germline editing, and most scientists cringe. The idea behind the notorious CRISPR-baby scandal, editing reproductive cells or embryos tinkers with DNA far beyond just the patient—any changes ...

Carl Zimmer recently reported in The New York Times about a new way Crispr could be used in new ways. “The groundbreaking thing about this work is that it now opens up the RNA world to Crispr ...

Shelby is an assistant editor for The Scientist. She earned her PhD from West Virginia University in immunology and microbiology and completed an AAAS Mass Media fellowship. View Full Profile. Learn ...

As the CRISPR/Cas systems integrate DNA from invading pathogens in chronical ... bacteria that is supposed to go and share the vector/plasmid through conjugation. The conjugation process is ...

Its CRISPR/Cas9 platform is a gene editing technology that allows for precise, directed changes to genomic DNA. The firm offers a portfolio of therapeutic programs across a broad range of disease ...