The first section of the book, Cellular DNA Replication, begins with an excellent overview of genome duplication by Thomas J. Kelly and Bruce Stillman, followed by chapters on specific steps in ...

Molecular and Cellular Biology 12 5736–5747 (1992). Langston, L. D. & O'Donnell, M. DNA replication: keep moving and don't mind the gap. Molecular Cell 23 155–160 (2006) doi:10.1016/j.molcel.

Taking the CBSE Class 12 Biology board exam? Here are a few common mistakes you need to stop making to boost your score as ...

the helix structure is unwound special molecules break the weak hydrogen bonds between bases, which are holding the two strands together this process occurs at several locations on a DNA molecule ...

A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication. Cell lines ...

DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of DNA DNA replication is the process by which a cell makes an identical ...

expanding our understanding of human biology -- and potentially leading to better medicines. DNA replication is happening continuously throughout the body, as many as trillions of times per day.

The central dogma of molecular biology describes the flow of genetic information within a biological system. It states that the genetic information encoded in DNA is transcribed into RNA, which is ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged DNA.

DNA replication, repair, and damage response, collectively called the 3Rs, support genome stability and faithful genetic inheritance. Proteins involved in the 3Rs are genome guardians that prevent a ...

Chair, Molecular Biology Program, SKI; Director, The Functional Genomics Initiative; Paul A. Marks Chair in Molecular Cell Biology Scientists know that cancer can result from mistakes in DNA repair.

The transfer of this principle to artificial cells is a challenge in synthetic biology. Advances in DNA nanotechnology now offer promising solutions. They allow the creation of novel transport ...