for example, owing to dysfunction of the breast cancer type 1 susceptibility protein (BRCA1). Indeed, mutations in BRCA1 are known to predispose individuals to hereditary breast and ovarian cancers.

She and her sister Lyndsay Cooper, 32, both carry a BRCA1 mutation, a genetic change that increases one’s risk for breast and ovarian cancer. This means they undergo surveillance, including ...

Genetics significantly impact cancer risk, particularly in inherited mutations like BRCA1/BRCA2, which increase ...

and it's known that it takes multiple mutations to form a cancer. However, in some women carrying high-risk genetic variants of BRCA1 and BRCA2, the researchers observed a few "extreme" examples ...

For example, mutations in the genes MLH1 ... and kidney dysfunction. However, BRCA1/2 and other cancer risk genes haven't traditionally been part of the carrier screening panels that are typically ...

Ethnicity can play a role in the odds of a person having these changes to the gene – for example people ... “Knowing that you’re BRCA1 positive, that you have a mutation that you may have ...