Because p62, one of the adaptors involved in directing substrates for autophagic degradation, has a ubiquitin-binding domain, researchers focused on ubiquitin as a sorting signal in autophagy.

Over time, the disease can also affect memory and lead to dementia. A similar condition called Lewy Body Dementia (LBD), ...

According to the findings, the p62 protein, which plays a crucial role in the cell's autophagy process, is abundant in micronuclei and affects their stability. Similar to the companion study ...