A research team affiliated with UNIST has unveiled an innovative technology to eliminate drug-resistant cancer cells using ...

Daily treatment ... STF-62247 induces autophagy — a process that has been implicated in a number of diseases including neuronal degeneration, infectious disease and cancer — in a HIF ...

whereas the inhibition of autophagy can sensitize cancer cells to chemotherapy to promote p53-induced apoptosis. Thus, manipulation of autophagy can determine cell-fate decisions in clinical settings.

Abstract Autophagy is a crucial quality control mechanism that degrades damaged cellular components through lysosomal fusion with autophagosomes ...

Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol ... is one of the main lines of treatment for high-risk cases of TC.

Understanding the mechanisms behind MRD formation is paramount to improving treatment outcomes in TC and many other forms of cancer ... rely on the activation of autophagy (or 'internal recycling ...

In their study, the researchers revealed that an autophagy pathway in astrocytes ... as a novel target for therapy. The ...

stabilizer TH-301 in models of pancreatic ductal adenocarcinoma (PDAC). It was seen that treatment with TH-301 led to significant dose-, time- and cell type-dependent decreases in viability.

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

fasting is a spiritual practice in various faiths and has been studied as a treatment for medical conditions like hypertension and cancer. Research on fasting for other health benefits ...