Although initially considered simply a degradative process, recent studies have revealed an integral role for autophagy in human pathophysiology. Accordingly, there has been a tremendous increase ...

Curcumin, the active ingredient in turmeric, has been reported in animal studies as an autophagy inducer. Yet, more human studies will be required; however, curcumin's properties as an anti ...

Longevity-promoting regimens, including caloric restriction and inhibition of TOR with rapamycin, resveratrol or the natural polyamine spermidine, have been associated with autophagy (a ...

Researchers from University of Athens and National Centre For Scientific Research “Demokritos” have reported preclinical data from a study that aimed to assess the novel cryptochrome-2 (CRY2) ...

Transient Ca 2+ fluctuations on the surface of the endoplasmic reticulum (ER) can induce liquid-liquid phase separation (LLPS) of the autophagy initiation complex FIP200, forming FIP200 puncta and ...