whereas the inhibition of autophagy can sensitize cancer cells to chemotherapy to promote p53-induced apoptosis. Thus, manipulation of autophagy can determine cell-fate decisions in clinical settings.
Targeting autophagy in this way is a promising approach ... as well as to improve the efficacy of cancer treatments. The study has been published in the scientific journal Nature Cell Biology.
it is possible to artificially trigger autophagy, which could then enable the degradation of deposits in neurodegenerative diseases such as Alzheimer's, or support cancer therapies. Recycling ...
Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers from Institute of Science Tokyo. Using a large ...
Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.
Researchers from University of Athens and National Centre For Scientific Research “Demokritos” have reported preclinical data from a study that aimed to assess the novel cryptochrome-2 (CRY2) ...