Several uncontrolled case series have described atypical subtrochanteric or femoral shaft fractures after long-term bisphosphonate therapy; the presumed mechanism is oversuppression of bone ...

Osteonecrosis of the jaw has been reported. Atypical femur fractures have been reported. Evaluate new thigh or groin pain to rule out an incomplete femoral fracture. Bisphosphonates included in ...

No cases of osteonecrosis of the jaw and no atypical femoral fractures occurred during the trial. A total of 11 participants died during the trial, 8 had a myocardial infarction, 7 had a stroke ...

Atypical femoral fractures are a potential side effect of the drug. "That's when the endocrinology people worked out that I was just one of the rare people that's had this," Ms May said.

Surgeons should aim to prevent intraoperative femur fractures by identifying high-risk patients and surgical risk factors. Sound change during broaching is key to know when to stop. KOLOA ...