Gap junctions are specialized structures that ... Studies have shown that Cx43 hemichannels contribute to astrocyte-mediated neurotoxicity in ALS, and the knockout of Cx43 in astrocytes can ...

astrocyte-to-astrocyte transmission through gap junctions, as well as paracrine release of ATP, might modulate synaptic biology. Nicholas Maragakis is an assistant professor of neurology at the ...

This review considers the role that optic nerve head astrocytes might play in the initiation of axon damage, based on the hypothesis that these cells are sensitive to mechanical or ischaemic ...