Apoptosis permits cell death without a concomitant inflammatory ... Defects in control of apoptotic pathways may contribute to a variety of diseases including cancer, autoimmune and ...

Ance-related pathway to death still occurred in Drosophila mutants that lacked important apoptosis, necrosis, and autophagy-related proteins. In all cases, erebosis persisted. In all, their findings ...

Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent ... release of caspase activators from mitochondria during apoptosis. Here we ...

Cell death is achieved by two fundamentally different mechanisms: apoptosis and necrosis. Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway ...

There are several programmed cell death pathways that lead to cellular self-destruction, either for developmental processes, tissue maintenance, or stress responses. These include apoptosis, ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed by a team led by Osaka Metropolitan University ...

Most people associate sunburns with DNA damage -- it's what we've been taught in textbooks and by dermatologists for years.

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

"RNA silencing and interferon signaling were previously considered as independent pathways ... response and apoptosis, with TRBP irreversibly increasing the programmed cell death of infected ...

The Overholtzer lab studies mechanisms of nutrient sensing and cellular responses to nutrient starvation, including the nutrient recycling pathway ... cancer. Cell biologist Michael Overholtzer ...

By blocking or inhibiting apoptosis—a type of programmed cell death—they discovered altered ... removal of unfit cells occurs via a specific pathway—the Smad/Foxo3/reactive oxygen species ...

The Overholtzer lab studies mechanisms of nutrient sensing and cellular responses to nutrient starvation, including the nutrient recycling pathway autophagy, scavenging pathways such as ...