we put in an enormous amount of work into confirming the specificity of the antibodies,” Solache explains. The company uses knock-out cell lines to eliminate doubts about cross reactivity ...

Antibodies that are cross-adsorbed against another species also need to show minimal cross-reactivity to immunoglobulins originating from that species, to allow researchers to select an antibody ...

1. Choosing the right target of interest Identifying the most effective target protein, or antigen, and understanding its complexity is key in choosing the right antibody. Homology with closely ...

He found that 45 of the 75 generated antibodies bound and neutralized α-LTX. Next, the researchers tested their top candidates against α-LTX from a different Latrodectus species to study their cross ...