Angelman syndrome is caused by a large deletion of the region of the maternal chromosome that contains UBE3A, or by a DNA sequence change (mutation) in the UBE3A gene inherited from the mother.

Many cases of Angelman syndrome can go undiagnosed because the disorder shares symptoms and characteristics with other conditions. Men and women are equally likely to experience the disorder.

For the first time, Colin Farrell has opened up his home and talked in-depth about life with his son James, who has Angelman ...

Just before Immy's third birthday, the family finally received an answer: Angelman syndrome, a rare neurogenetic disorder causing global developmental delays. The diagnosis left them wondering if ...

Ionis has committed to a phase 3 programme for its antisense therapy for rare genetic disorder Angelman syndrome, just weeks after Biogen decided against exercising an option to license the drug.

Considering taking supplements to treat angelman syndrome? Below is a list of common natural remedies used to treat or reduce the symptoms of angelman syndrome. Follow the links to read common ...

to treat Angelman syndrome (AS). "This program has consistently delivered remarkable animal data, reinforcing its potential as a groundbreaking treatment," said Dr. Donald Kohn, Distinguished ...

We each get two copies of every gene - one copy from each of our parents. But what happens when one of these genes has been "turned off", or imprinted, and the remaining gene is defective?