Renal hypoperfusion occurs as a result of reduced cardiac output, resulting in the activation of the renin–angiotensin–aldosterone system, which compensates for the hypoperfusion. However ...

I present the evidence that renal dysfunction is a common and powerful cardiovascular risk factor and that treatment strategies intervening in the renin–angiotensin–aldosterone system can be ...

The first recipient of a gene-edited pig kidney died from cardiac causes 52 days after xenotransplantation. The world's first ...

Aldosterone might have a role in the progression of renal disease; therefore, van den Meiracker et al. investigated whether adding the aldosterone receptor antagonist spironolactone to renin ...

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Baxdrostat is a drug that reduces aldosterone levels in the body to treat high blood pressure and other conditions. It's an ...

Aldosterone antagonists (spironolactone ... New York Heart Association functional class IV symptoms, preserved renal function and a normal potassium concentration. Spironolactone was investigated ...

Aldosterone tells the kidney and other organs to retain sodium, which helps maintain the existing fluid in the body. However, when aldosterone is inappropriately high, a condition called primary ...

It suppresses the renin-angiotensin-aldosterone system ... Postsympathectomy. Renal or hepatic impairment. Dialysis (esp. high-flux membrane). Gout. Asthma. SLE. Acute myopia.

The primary renal compensatory mechanism is retention of sodium and water through activation of the renin-angiotensin-aldosterone system. Angiotensin also increases peripheral vascular resistance ...