Adenylosuccinate lyase deficiency (ADSLD) is a rare genetic disorder that affects purine metabolism, leading to various neurodevelopmental issues. Purines are essential building blocks for DNA and ...

deficiency, tuberous sclerosis, adenylosuccinate lyase deficiency, and cyclin-dependent kinase-like 5 (CDK). KD contraindications include errors related to lipid and pyruvate metabolisms.