Actin serves many functions ... "A fascin protein can accommodate all kinds of imperfections. It acts like a molecular hinge that can hold a number of intermediary positions between open and closed.

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

To gain more molecular insight into this process, we focused on actin proteins." Actin is a component of the cell's structure ...

No biological system has been studied by more diverse approaches than the actin-based molecular motor myosin. Biophysics, biochemistry, physiology, classical genetics and molecular genetics have ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

The paper S. Kaur et al., “An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis,” eLife, 3:e00829, 2014. For decades, scientists observed clathrin-mediated ...

Scientists reveal how filopodia help cancer spread. The breakthrough could improve treatments that stop cancer cells from invading tissues.

the function of molecular machines essential to the organization and utilization of the actin and microtubule cytoskeleton of eukaryotic cells. All of the processes that we study involve dynamic ...

The ‘Actin-based molecular machines’ group of Academy Professor Pekka Lappalainen at Institute of Biotechnology is now inviting applications for post-doctoral researcher cell biology, biochemistry, or ...

The mechanism of molecular motors involves a cyclic interaction between the motor domain and the cytoskeletal filament (actin or microtubule). ATP hydrolysis induces conformational changes in the ...