Two classes of antihypertensives target angiotensin II, either through preventing its formation by inhibiting ACE or by preventing angiotensin II from binding to receptors on blood vessels.

In addition to their capacity to lower systemic blood pressure, angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-II receptor blockers (ARBs) are thought to have specific ...

[1] When administered in appropriate dosages, all ACE inhibitors are effective antihypertensives both as monotherapy and in combination therapy, tolerance to the antihypertensive effect does not ...

Antihypertensives are very common ... Diuretics are often prescribed as a first-line treatment for hypertension. ACE inhibitors block the formation of a natural chemical that narrows blood ...

The combination of ACE inhibitors and ARBs is not recommended because of the added adverse effects. Aldosterone antagonists (spironolactone and epleronone) have additional antihypertensive effects ...