Single guide RNAs (sgRNAs) designed and built to guide Cas9 to bind and cut desired intronic regions in the EML4 and ALK gene targets, trigger the paracentric genomic rearrangement event upon co ...

As a consequence of these gene profiling studies ... in melanoma and the use of crizotinib (a MET inhibitor that blocks ALK) for the treatment of non-small cell lung carcinoma with ALK ...

can be removed with surgery (resectable), and does not have genetic mutations in the EGFR gene or genetic mutations called rearrangements in the ALK gene. Your healthcare professionals should give you ...

MADISON, Wis. (WMTV) - A fundraiser for a rare genetic form of lung cancer happened Sunday, raising money for greater research and awareness of the disease. Supporters came through rain and shine ...

The company secured global rights to the university's patents related to its Reqorsa gene therapy (quaratusugene ozeplasmid), along with anaplastic lymphoma kinase (ALK)-inhibitors for treating ...