Somatic diversification of receptors is one of many molecular mechanisms that evolved to support the clonally dependent vertebrate adaptive immune system. The cell types and cell communication ...

The unique feature of an adaptive ... and other types of innate immune cell and humoral components, which have important inductive or effector roles to provide protective immunity 4.

The adaptive immune system is an antigen-specific structure ... that risk for islet autoimmunity drastically increased in DR3/4-DQ2/DQ8 siblings who shared both HLA haplotypes identical by descent ...