While unrelated human MSCs and xenogeneic rat MSCs did not elicit human T-cell activation, unrelated human dermal fibroblasts and murine NIH-3T3 cells elicited T-cell activation (Figure 8).

The question of how these kinases are activated attracted a considerable amount of attention. Work in our laboratory led to the identification of two forms of potent MAP kinase activator in Swiss 3T3 ...

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.